Table 4.

Mean plasma concentration of naloxone at 30 and 60 min post-injection. ¹

Dose of Naloxone mg/kg	Mean Plasma Conc NLX ± SD [Range] (ng/mL) 30 min Post-IM 1	Mean Plasma Conc NLX ± SD [Range] (ng/mL) 60 min Post-IM
0.06	4.6 ± 1.9 [3.3–5.9]	2.3 ± 2.4 [0.7–4.0]
0.14	16.8 ± 2.3 [15.1–18.4]	8.1 ± 1.0 [7.4–8.8]
0.28	43.4 ± 19.0 [30.0–56.8]	23.2 ± 1.6 [22.0–24.3]

¹ Data is mean ± SD [range] for PK studies (n = 1 per monkey, as summarized in Table 1).