Table 1. Physicochemical Properties, Encapsulation Efficiency, and Drug Loading Content of MF NPs (n = 3, mean ± s.d.).
| formulation | mean diameter (nm) | polydispersity index (PDI) | zeta potential (mV) | encapsulation efficiency (%)a | drug loading content (%)b |
|---|---|---|---|---|---|
| MF NPs | 117 ± 13 | 0.26 ± 0.02 | –32 ± 1.2 | 90 ± 2.1 | 22.4 ± 0.5 |
a
Encapsulation efficiency (%) = (amount of drug in nanoparticles/amount of drug fed initially) × 100.
b
Drug loading content (%) = [amount of drug/(amount of drug + amount of polymer)] × 100.