. 2020 Mar 25;5(13):7432–7439. doi: 10.1021/acsomega.0c00111

Table 3. Correlation Coefficient (R²) Values of Various Release Kinetic Models in 1% SDS Buffers (pH 7.4 and pH 6.4) for Freeze-Dried MF NPs.

	zero order	first order	Higuchi model	Korsmeyer–Peppas model
cryoprotectant [8% (w/v)]	R²	R²	R²	n	R²
sucrose pH 7.4	0.907	0.955	0.984	0.57	0.934
sucrose pH 6.4	0.971	0.975	0.952	0.66	0.985
mannitol pH 7.4	0.975	0.988	0.950	0.46	0.953
mannitol pH 6.4	0.954	0.976	0.940	0.63	0.980

Table 3. Correlation Coefficient (R2) Values of Various Release Kinetic Models in 1% SDS Buffers (pH 7.4 and pH 6.4) for Freeze-Dried MF NPs.