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. 2020 Mar 23;35(1):773–785. doi: 10.1080/14756366.2020.1740693

Figure 7.

Figure 7.

(A) Cells were treated with compound 12 alone (4 μM), 3MA (500 μM, pro-incubated for 1 h), compound 12 combined with 3MA and the Annexinv-FITC staining was used to evaluate the apoptosis ratio. (B) The activation of Bax, Bcl2, cl-PARP were determined by the western blot after SGC-7901 cells were exposed to compound 12 for 48 h with or without of 3MA (500 μM). *p < 0.05, ***p < 0.001 compared with the control group.