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. 2020 Mar 11;9(1):1736935. doi: 10.1080/20013078.2020.1736935

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Mapping of the prostate cancer proteome in EV-enriched fractions. LC-MS/MS data from EV-enriched fractions from prostate cancer patients pre- and post-treatment are compared by (a) principle component analysis and (b) volcano plot analysis. Proteins related to prostate (pre-treatment) and bladder and kidney (post-treatment) tissue are highlighted. (c) LC-MS/MS data from EV-enriched fractions from patients with benign prostatic hyperplasia (BPH) and prostate cancer (PC) as compared by principle component analysis. (d) Venn diagram displaying EV-enriched proteins enriched in prostate cancer EV prior to treatment versus after treatment and versus benign prostatic hyperplasia.