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. 2020 May 7;55(5):2000524. doi: 10.1183/13993003.00524-2020

TABLE 2.

Laboratory findings in patients with COVID-19 pneumonia

Characteristics Total Deceased Survivors p-value
Patients 179 21 158
White blood cells ×109cells·L−1 5.3 (3.9–7.8) 8.9 (4.8–13.1) 5.1 (3.8–7.3) 0.003
Neutrophils ×109cells·L−1 4.0 (2.7–6.6) 7.7 (3.0–11.5) 3.9 (2.6–6.1) 0.007
Lymphocytes ×109cells·L−1 0.8 (0.6–1.1) 0.7 (0.5–0.8) 0.8 (0.6–1.1) 0.046
T-cell subsets
 CD3+CD4+ cells·μL−1 114.3 (62.9–195.3) 68.0 (55.1–148.8) 128.3 (73.5–201.7) 0.066
 CD3+CD8+ cells·μL−1 75.5 (45.5–125.0) 47.9 (25.4–73.8) 104.5 (58.5–142.7) 0.001
C-reactive protein mg·L−1 39.8 (20.6–97.8) 86.4 (37.9–105.5) 36.0 (19.3–91.0) 0.012
Procalcitonin ng·mL−1 0.1 (0.0–0.2) 0.1 (0.1–0.5) 0.1 (0.0–0.2) 0.013
Cardiac troponin I ng·mL−1 0.0 (0.0–0.1) 0.1 (0.0–0.8) 0.0 (0.0–0.0) <0.001
Myoglobin ng·mL−1 36.9 (18.4–124.0) 162.0 (48.5–342.8) 32.3 (15.5–60.3) <0.001
Brain natriuretic peptide pg·mL−1 645.0 (110.0–1504.0) 970.0 (620.5–3531.0) 390.0 (58.0–1118.5) 0.004
Albumin g·L−1 33.2 (30.7–36.4) 33.2 (31.2–35.6) 33.0 (30.6–38.1) 0.764
Total bilirubin μmol·L−1 8.9 (6.6–12.5) 9.6 (8.3–16.3) 8.7 (6.5–12.3) 0.146
Direct bilirubin μmol·L−1 2.5 (1.8–3.9) 3.1 (2.3–6.1) 2.4 (1.8–3.8) 0.101
Alanine aminotransferase U·L−1 22.0 (15.0–40.0) 27.0 (20.0–37.0) 22.0 (14.0–40.5) 0.233
Aspartate aminotransferase U·L−1 30.0 (19.0–43.0) 40.0 (27.0–61.5) 27.5 (19.0–42.0) 0.010
γ-Glutamyltranspeptidase U·L−1 29.0 (17.0–52.5) 23.0 (16.5–42.0) 29.0 (17.0–54.5) 0.518
Creatinine μmol·L−1 66.5 (55.8–82.0) 95.0 (63.0–112.0) 65.0 (55.0–80.0) 0.001
D-dimer mg·L−1 0.5 (0.3–1.7) 1.1 (0.4–10.5) 0.5 (0.3–1.2) 0.011
Prothrombin time s 13.7 (12.4–15.4) 13.9 (12.3–16.3) 13.7 (12.4–15.2) 0.758
Activated partial thromboplastin time s 35.6 (31.0–39.4) 37.8 (30.8–41.5) 35.3 (30.9–39.1) 0.383
PaO2 mmHg 72.0 (57.0– 88.0) 56.0 (49.0 –71.0) 74.5 (59.0–92.0) 0.001
PaCO2 mmHg 37.0 (33.0– 41.0) 34.0 (29.0–41.0) 37.0 (34.0–41.0) 0.068
PaO2:FIO2 mmHg 249.6±106.1 185.5±64.8 261.5±108.2 0.002

Data are presented as n, median (interquartile range) or mean±sd, unless otherwise stated. PaO2: arterial oxygen tension; PaCO2: arterial carbon dioxide tension; FIO2: inspiratory oxygen fraction.