TABLE 3.

Univariate analysis of mortality risk factors for patients with COVID-19 pneumonia

Characteristics	Deceased	Survivors	OR (95%CI)	p-value
Patients n	21	158
Age group years
0–49	0	31.0	0.000 (0.000–)	0.997
50–64	19.0	38.6	2.673 (0.859–8.318)	0.090
≥65	81.0	30.4	9.740 (3.113–30.476)	<0.001
Underlying diseases
Hypertension	61.9	28.5	4.081 (1.584–10.510)	0.004
Cardiovascular or cerebrovascular diseases	57.1	10.8	11.059 (4.068–30.063)	<0.001
Symptoms
Dyspnoea	85.7	44.9	7.352 (2.082–25.966)	0.002
Fatigue	61.9	36.7	2.802(1.096–7.160)	0.031
Sputum production	57.1	27.2	3.566 (1.403–9.061)	0.008
Headache	23.8	7.6	3.802 (1.187–12.177)	0.025
Respiratory rate >20 breaths·min−1	47.6	31.0	2.022(0.806–5.076)	0.134
White blood cells ×109 cells·L−1
>10	33.3	12.7	3.450 (1.242–9.580)	0.017
4–10	52.4	60.1	1.371 (0.550–3.418)	0.499
<4	14.3	27.2	0.446 (0.125–1.590)	0.213
Neutrophils ×109 cells·L−1
>6.3	57.1	24.7	4.068 (1.594–10.382)	0.003
1.8–6.3	33.3	65.2	0.267 (0.102–0.700)	0.071
<1.8	9.5	10.1	0.934 (0.199–4.384)	0.931
Lymphocytes <1.1×109 cells·L−1	90.5	72.2	3.667(0.820–16.400)	0.089
CD3+CD8+ T-cells ≤75 cells·μL−1	78.9	40.0	5.625 (1.664–19.013)	0.005
C-reactive protein ≥10 mg·L−1	95.2	87.3	2.901 (0.368–22.878)	0.312
Procalcitonin ≥0.5 ng·mL−1	21.1	9.9	2.438 (0.631–9.414)	0.196
Cardiac troponin I ≥0.05 ng·mL−1	61.5	17.9	7.314 (1.832–29.210)	0.005
Myoglobin >100 ng·mL−1	64.3	18.4	8.000 (2.157–29.671)	0.002
Brain natriuretic peptide >100 pg·mL−1	94.1	67.6	7.680 (0.909–64.906)	0.061
Aspartate aminotransferase >40 U·L−1	47.6	29.9	2.134 (0.848–5.373)	0.108
Creatinine ≥133 μmol·L−1	19.0	2.1	11.137 (2.296–54.028)	0.003
D-dimer ≥0.5 mg·L−1	76.2	47.9	3.474 (1.152–10.481)	0.027
PaO2 mmHg
≥80	14.3	41.7	0.233 (0.065–0.840)	0.026
60–79	28.6	32.4	0.834 (0.298–2.334)	0.730
<60	57.1	25.9	3.810 (1.451–10.004)	0.007
PaO2:FIO2 <200 mmHg	47.6	29.2	2.204 (0.854–5.684)	0.102

Data are presented as %, unless otherwise stated. P_aO2: arterial oxygen tension; F_IO2: inspiratory oxygen fraction.