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Thermodynamic parameters and binding affinities of the BSA interaction with rosmarinic and caffeic acid.
| Ligand | n | ΔΗ (cal/mol) | ΔG (cal/mol) | ΔS (cal/mol/deg) | Ka (M) | Kd (μΜ) | |
|---|---|---|---|---|---|---|---|
| Rosmarinic acid | 1.45 | −6008 ± 302.8 | −5280 | −2.44 | 7390 ± 593 | 135.3 ± 10.8 | |
| Caffeic acid | 1.8 | −14680 ± 1139 | −3832 | −36.4 | 639 ± 65.3 | 1564.9 ± 156.7 | |
