Table 3.
Binding affinities of AM-879 were measured by TR-FRET against ATAD2 and the first and second bromodomains of BRD2, BRD3 and BRD4.
| IC50 (μM) | |
|---|---|
| ATAD2 | 3.56 |
| BRD2(1) | >50 |
| BRD2(2) | >50 |
| BRD3(1) | >50 |
| BRD3(2) | >50 |
| BRD4(1) | >50 |
| BRD4(2) | >50 |
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