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. 2020 Mar 17;25(6):1370. doi: 10.3390/molecules25061370

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effect of 14-OMeC6SU (A) on rat gastrointestinal transit compared to C6SU (B), codeine (C) and morphine (D). The figure represents the inhibition of gastrointestinal transit in percentage (means ± S.E.M.) of total length compared to vehicle treated group in the presence of 14-OMeC6SU, C6SU and morphine in the indicated dosages. * indicates the significant difference compared to control (One-way ANOVA, Tukey’s multiple comparisons post hoc test, P < 0.001). * P < 0.05; ** P < 0.01; *** P < 0.001.