Table 6.
Antinociceptive potencies (ED50) of 14-OMeC6SU and codeine against radiant heat induced nociception in rat tail-flick test after 30 and 60 min of s.c. administration. As a reference compound morphine was also indicated.
| ED50 (95% Confidence Limit) (µmol/kg) | ||
|---|---|---|
| Time After s.c. Administration (min) | ||
| Compounds | 30 | 60 |
| 14-OMeC6SU | 5.34 a (3.14–9.06) |
9.88 (7.47–13.06) |
| Codeine | 54.01 a (33.97–85.88) |
89.86 (61.54–131.2) |
| Morphine 1 | 6.87 a (4.59–10.27) |
14.17 (10.24–19.62) |
1 [23]; a Peak of effect.