Table 2: Manually curated resources used to construct EMCON.

A total of seven resources that manually tag GeneID’s to articles within PubMed were integrated to serve as the initial dataset for building EMCON. Over 1.2 million articles make up the naive GeneID-MeSH network with over 7 million genes for over 14K species.

Gene and gene product databases	Number of articles	Number of GeneIDs in articles	Number of species across GeneIDs
gene2pubmed [33]	1,062,713	5,565,651	12,782
Gene Reference into Function (generif) [45]	705,441	90,329	1,913
Comparative Toxicogenomics Database (CTD) [36]	58,180	43,298	76
Universal Protein Resource (UniProt/Swiss-Prot) [37]	950,989	5,156,248	12,555
Reactome [38]	15,650	11,110	9
Rat Genome Database (RGD) [40]	834,585	87,874	7
Mouse Genome Informatics (MGI) [43]	181,519	42,020	1
Total Unique	1,238,879	7,074,406	14,126