Comparison 3. HCSE versus ß‐hydroxyethyl‐rutosides.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Reduction of circumference at ankle (mm)	2	60	Mean Difference (IV, Random, 95% CI)	2.38 [‐1.47, 6.23]
2 Reduction of circumference at calf (mm)	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
3 Reduction of leg pain (VAS)	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
4 Leg volume (ml)	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
5 Reduction of oedema (VAS)	1		Mean Difference (IV, Random, 95% CI)	Totals not selected