Fox 1990.
Methods | Cross‐over RCT of prone and supine positions | |
Participants | Included: 25 preterm infants with a gestational age of 36 weeks or less, who were receiving intermittent mandatory ventilation and/or CPAP and supplemental oxygen for respiratory distress syndrome, and had an umbilical artery oxygen tension catheter in situ Excluded: infants receiving paralysing drugs Mean gestational age: 31 weeks; mean age: 58 hours; mean weight: 1633 g Setting: level III NICU, US |
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Interventions | All in incubators, on water mattress with head elevated 30 degrees, infants were allowed to settle to sleep after positioning before data collection commenced Ventilatory parameters and FiO2 remained unchanged | |
Outcomes | PaO2 Sampling occurred every 30 seconds for 15 minutes in each position; all data collected within a 1‐hour period |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | First position randomly assigned by coin toss |
Allocation concealment (selection bias) | Unclear risk | Not stated |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not stated |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Appears to be no loss to follow‐up |