McEvoy 1997.

Methods	Alternately allocated cross‐over trial of prone and supine positions
Participants	Included: 55 infants with a birth weight less than 1000 g, a diagnosis of respiratory distress syndrome, a FiO2 of more than 0.21 at 28 days or older, and a chest radiograph consistent with chronic lung disease Excluded: infants with multiple congenital anomalies, congenital heart disease, culture proven sepsis, evidence of seizure activity, or grade IV intra‐ventricular haemorrhage Mean gestational age: 26.0; mean birth weight: 775 g; mean age: 42.0 days; mean weight: 1147 g; mean FiO2: 0.30; ventilated: 17 Setting: NICUs, hospital and medical centre, USA
Interventions	1 hour in each position; alternatively and consecutively monitored after a 10‐minute stabilisation period in each position before monitoring was commenced; all were quietly asleep
Outcomes	SaO2; heart rate; respiratory rate; hypoxaemia (SaO2 < 80% at 0 to 45 s)
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	Alternate allocation was used
Allocation concealment (selection bias)	High risk	Alternate allocation was used
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not stated
Incomplete outcome data (attrition bias) All outcomes	Low risk	Appears to be no loss to follow‐up