Mizuno 1999.
| Methods | Cross‐over RCT of prone and supine positions | |
| Participants | Included: 7 very low birthweight infants with radiographic and clinical evidence of chronic lung disease, requiring ventilatory support and a feeding volume of more than 100 ml a day
Excluded: not stated Mean gestational age: 26.6 weeks; mean birth weight: 845 g; mean age: 57.4 days; mean weight: 1018 g; mean FiO2: 0.24 Setting: not stated |
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| Interventions | The infant was settled into position for at least 1 hour before being fed nasogastrically over 1 hour | |
| Outcomes | SaO2; tcPCO2; tidal volume; minute ventilation; spontaneous respiratory rate; pulmonary resistance Measured 10 minutes before and during feeding (20 minutes, 40 minutes and end of feeding) when infants were quiet and awake |
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| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Not stated |
| Allocation concealment (selection bias) | Unclear risk | Not stated |
| Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not stated |
| Incomplete outcome data (attrition bias) All outcomes | Low risk | Appears to be no loss to follow‐up |