Study	Reason for exclusion
Bagga 2003	Design: Prospective clinical trial in children.
Bakir 1996	Design: Case‐series.
Banfi 1991	Design: Retrospective case‐control study.
Beaufils 1978	Design: Retrospective case‐control study.
Bolton 1977	Design: Retrospective study.
Chan 1991	Design: Retrospective case‐control study.
Crenshaw 1999	Design: Retrospective case‐control study.
Dantal 1998	Design: Case‐report.
Dudar 2004	Design: Retrospective study.
El‐Reshaid 1995	Design: Case‐series.
Emre 2001	Design: Prospective clinical trial in children, Not a RCT.
Garin 1988	Design: Cross‐over RCT in children, median age 12 years (3‐18).
Goumenos 2006	Design: Retrospective cohort study.
Grcevska 2006	Design: Retrospective cohort study.
Gulati 2000	Design: Prospective study in children, not a RCT.
Heering 2004	Design: RCT. Patients: 57 nephrotic adults with FSGS, mean age 47 ± 15 years. Interventions: Group 1 (n = 34) prednisolone + aspirin, group 2 (n = 23) prednisolone + chlorambucil. Duration: 6‐12 weeks, follow‐up 4 years. Outcome measures: CR, PR, ESKD, creatinine, cholesterol, proteinuria. Results: group 1: CR 8/34, PR 13/34, ESKF 4/34; group 2: CR 4/23, PR 11/23, ESKD 5/23.
Ittel 1995	Design: Case‐series.
Lee 1995	Design: Multicentre, prospective interventional study, not a RCT.
Lieberman 1996	Design: Randomised double‐blind placebo controlled trial. Patients: Children aged 6 months to 21 years.
Medizábal 2005	Design: Prospective clinical trial, not a RCT.
Meyrier 1986	Design: Case‐series.
Meyrier 1989	Design: Prospective interventional study, not a RCT.
Meyrier 1994	Design: Case‐series.
Mowry 1993	Design: Retrospective case‐control study.
Nagai 1994	Design: Retrospective case‐control study.
Pei 1987	Design: Retrospective case‐control study.
Ponticelli 1999	Design: Retrospective case‐control study.
Raafat 2004	Design: Prospective clinical trial, not a RCT.
Rydel 1995	Design: Retrospective clinicopathological study.
Tarshish 1996	Design: RCT in children.
Walker 1990	Design: Randomised cross‐over study in adults and children. Patients: An unknown number of patients received CSA and warfarin, and in the other group an unknown number of patients received warfarin alone.
Xia 2003	Design: Prospective clinical trial in children