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. 2008 Jul 16;2008(3):CD003233. doi: 10.1002/14651858.CD003233.pub2

Bhamik 2002.

Methods Design: Open RCT
Participants
  1. Inclusion criteria: biopsy proven primary FSGS, therapy‐resistant to oral prednisolone.

  2. Country: India.

  3. Number: 25 patients.

  4. Age: 3 to 49 years.

Interventions Treatment group 
 CSA plus oral prednisolone 10‐40 mg/d for 6 months.
Control group 
 Methylprednisolone 250‐750 mg IV daily for 7 days followed by weekly administration for at least 12 weeks.
Outcomes
  1. Number with CR, PR with stable SCr.

  2. ESKD within 3 years.

  3. Decline in CrCl.

Notes
  1. Previous prednisolone dose 2 mg/kg/d for 8 weeks.

  2. ESKD: 1/13 in the treatment group and 4/12 in the control group.

Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate