Imbasciati 1980.

Methods	Design: Open RCT Duration: 6 months
Participants	Inclusion criteria: Biopsy‐proven FSGS, proteinuria > 1 g/d, SCr < 2 mg/dL. Country: Italy. Number: Treatment group (8), control group (7).
Interventions	Treatment group IV methylprednisolone/oral prednisolone plus chlorambucil. Control group No specific treatment.
Outcomes	Number with CR: proteinuria < 100 mg/d. Number with PR: persistent proteinuria but < 50% of baseline value and worsening kidney function.
Notes	Reported results are defined as "preliminary". No length of follow‐up.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ Adequate