Skip to main content
. 2011 Nov 9;2011(11):CD002855. doi: 10.1002/14651858.CD002855.pub4

Comparison 1. combined regimen mifepristone/prostaglandin: dose of mifepristone.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 failure to achieve complete abortion 6   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
1.1 all 6 6841 Risk Ratio (M‐H, Fixed, 95% CI) 0.90 [0.77, 1.05]
1.2 600mg vs 200mg 4 3494 Risk Ratio (M‐H, Fixed, 95% CI) 1.07 [0.87, 1.32]
1.3 200mg vs 100 mg (>49 days) 1 1182 Risk Ratio (M‐H, Fixed, 95% CI) 0.89 [0.61, 1.29]
1.4 600mg vs 200mg with gemeprost 1mg/pv 2 1685 Risk Ratio (M‐H, Fixed, 95% CI) 1.02 [0.72, 1.45]
1.5 200mg vs 100 mg (</=49 days) 1 941 Risk Ratio (M‐H, Fixed, 95% CI) 0.79 [0.47, 1.33]
2 side effects 2   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
2.1 nausea 2   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.2 vomiting 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.3 diarrhoea 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3 time until passing of conceptus > 3‐6 hours 2 1116 Risk Ratio (M‐H, Fixed, 95% CI) 0.89 [0.74, 1.07]
4 ongoing pregnancy 5   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
5 surgical evacuation 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only