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. 2011 Nov 9;2011(11):CD002855. doi: 10.1002/14651858.CD002855.pub4

Comparison 2. combined regimen mifepristone/prostaglandin: dose of prostaglandin.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 failure to achieve complete abortion 4   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
1.1 gemeprost 1 mg vs 0.5 mg 2 1034 Risk Ratio (M‐H, Fixed, 95% CI) 0.43 [0.31, 0.59]
1.2 misoprostol 800po or pv vs 400po 2 934 Risk Ratio (M‐H, Fixed, 95% CI) 0.83 [0.53, 1.31]
2 side effects 2 2802 Risk Ratio (M‐H, Fixed, 95% CI) 1.10 [0.95, 1.27]
2.1 nausea 2 934 Risk Ratio (M‐H, Fixed, 95% CI) 1.03 [0.85, 1.25]
2.2 vomiting 2 934 Risk Ratio (M‐H, Fixed, 95% CI) 1.21 [0.90, 1.64]
2.3 diarrhoea 2 934 Risk Ratio (M‐H, Fixed, 95% CI) 1.13 [0.81, 1.56]
3 women dissatisfied with the procedure 2 931 Risk Ratio (M‐H, Fixed, 95% CI) 1.06 [0.76, 1.50]
4 ongoing pregnancy 2 933 Risk Ratio (M‐H, Fixed, 95% CI) 0.10 [0.01, 0.76]
4.1 misoprostol 800mcg vs 400 mcg 2 933 Risk Ratio (M‐H, Fixed, 95% CI) 0.10 [0.01, 0.76]
5 surgical evacuation 2 934 Risk Ratio (M‐H, Fixed, 95% CI) 0.83 [0.53, 1.31]
5.1 misoprostol 800mcg vs 400mcg 2 934 Risk Ratio (M‐H, Fixed, 95% CI) 0.83 [0.53, 1.31]