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. 2011 Nov 9;2011(11):CD002855. doi: 10.1002/14651858.CD002855.pub4

Comparison 19. combined regimen methotrexate/prostaglandin: route of prostaglandin (misoprostol).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 failure to achieve complete abortion 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
2 side effects 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
2.1 nausea 1 309 Risk Ratio (M‐H, Fixed, 95% CI) 1.09 [0.84, 1.42]
2.2 vomiting 1 309 Risk Ratio (M‐H, Fixed, 95% CI) 1.02 [0.67, 1.56]
2.3 diarrhoea 1 309 Risk Ratio (M‐H, Fixed, 95% CI) 1.40 [0.94, 2.07]