| Methods |
computer generated random numbers for the first 300 women, envelopes were shuffled in batches of 20 and numbered consecutively for the reminders
no blinding for clinical staff |
| Participants |
800 pregnant women </= 63 days of amenorrhoea in Edinburgh/Scotland |
| Interventions |
mifepristone 200mg (all) followed by:
group 1: gemeprost 0.5mg vaginal and 3 tabs placebo after 48 hours
group 2: misoprostol 600mcg oral and vaginal examination after 48 hours |
| Outcomes |
complete, incomplete and missed abortion
ongoing pregnancy
side effects |
| Notes |
power calculation (80% to detect 5% difference)
placebos were not identical to misoprostol
1 woman needed blood transfusion (group 2) |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |
