| Methods |
random number tables in blocs of ten, sealed opaque envelopes prepared by person not involved in the trial |
| Participants |
80 pregnant women, ≤ 49 days pregnant, single pregnancy, confirmed by ultrasound, at the University hospital Pittsburgh, USA;
exclusion criteria: contraindication to mifepristone/misoprostol administration, haemoglobin < 10 gm/dL, cardiovascular disease, coagulopathies, IUCD in situ, breast feeding |
| Interventions |
mifepristone 100mg (all)
after 2 days, home administration:
group 1: misoprostol 400mcg oral
group 2: misoprostol 800mcg vaginal |
| Outcomes |
complete abortion, onset of bleeding &cramping, duration of bleeding, side effects |
| Notes |
power calculation power calculation (80% power, significance level of 0.05)
no major complications were reported |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Low risk |
A ‐ Adequate |
