Guest 2007.
Methods | computer generated fixed blocks of 20; 1:1 randomisation; sealed opaque envelopes | |
Participants | 450 women aged 24‐26 years; no more than 63 days gestation confirmed by US (average 51 days of gestation); exclusion criteria: contraindications for study medication, breastfeeding, Hbg<10, coagulopathy or treatment with anticoagulants, IUD in situ, presence of cardiovascular disease, ectopic pregnancy; study conducted between September 2003 ‐ March 2005 | |
Interventions | mifepristone 200mg followed by: group 1: 800mcg vaginal misoprostol after 6 hours group 2: 800mcg of vaginal misoprostol after 36‐48 hrs later |
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Outcomes | complete abortion, side effcets, acceptability | |
Notes | ITT analysis | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Low risk | A ‐ Adequate |