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. 2011 Nov 9;2011(11):CD002855. doi: 10.1002/14651858.CD002855.pub4

Guest 2007.

Methods computer generated fixed blocks of 20; 1:1 randomisation; sealed opaque envelopes
Participants 450 women aged 24‐26 years; no more than 63 days gestation confirmed by US (average 51 days of gestation); exclusion criteria: contraindications for study medication, breastfeeding, Hbg<10, coagulopathy or treatment with anticoagulants, IUD in situ, presence of cardiovascular disease, ectopic pregnancy; study conducted between September 2003 ‐ March 2005
Interventions mifepristone 200mg followed by:
group 1: 800mcg vaginal misoprostol after 6 hours
group 2: 800mcg of vaginal misoprostol after 36‐48 hrs later
Outcomes complete abortion, side effcets, acceptability
Notes ITT analysis
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Low risk A ‐ Adequate