Hamoda 2005.
Methods | random number tables; sealed opaque envelopes | |
Participants | 340 women, average age 24 years randomised; average gestational age 65‐68 days. Exclusion criteria: <16 years, severe asthma,haemorrhagic disorders and treatment with anticoagulants, known allergy to prostaglandins, history of cardiac disease, smoking over the age of 35 years with ECG abnormalities, breastfeeding. study conducted at Aberdeen Royal Infermary, UK, from July 2002 ‐ October 2003 |
|
Interventions | mifepristone 200 mg, followed 36‐48 hours after by: group 1: 600mcg sublingual misoprostol, followed 3 hours later by 400mcg (if 9‐13 weeks gestation, a third dose of 400mcg was administered) group 2: 800mcg vaginal misoprostol, followed 3 hours later by 400mcg (if 9‐13 weeks gestation, a third dose of 400mcg was administered) |
|
Outcomes | complete/incomplete abortion, missed abortion, continuing pregnancy | |
Notes | No ITT; LTFU identical (13) in each group (total 26) | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Low risk | A ‐ adequate |