| Methods |
women were randomly divided into 2 groups by 2:1 ratio |
| Participants |
Multicentre trial in 9 hospitals in Hebei,China; 1612 pregnant women ≤ 49 days of amenorrhoea, confirmed by ultrasound; without clinical or haematological abnormalities,contraindication for the study medication or IUD in situ. |
| Interventions |
group 1:
day 1: mifepristone 50 mg/po 12 hours apart (= total of 100 mg)
day 2 to day 7: mifepristone 25 mg/po daily (= total of 250 mg)
day 3: misoprostol 600 mcg/po
day 4 to day 6: misoprostol 200 mcg daily (= total of 600 mcg)
group 2:
day 1: mifepristone 50 mg/po then 25 mg/12 hourly/4 times (= total of 150 mg)
day 3: misoprostol 600 mcg/po |
| Outcomes |
complete/incomplete abortion, duration of bleeding, resuming of menses, side effects |
| Notes |
post‐randomisation exclusion, protocol deviation, loss to follow‐up not mentioned
no mentioning of major complications |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |
