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. 2012 Feb 15;2012(2):CD003306. doi: 10.1002/14651858.CD003306.pub2

Kristjansson 1995.

Methods Randomised prospective study, initially by Mansson, 1989 with 2 subsequent papers published with longer follow‐up: Kristjansson, 1995a (primary reference) and 1995b.
Mansson 1989 
 Mean follow‐up: Ileal conduit 67 months, colonic conduit 66 months and caecal reservoir 62 months 
 Drop‐outs: none
Kristjansson 1995a (primary reference) 
 Mean follow‐up: Ileal conduit 121 months, colonic conduit 117 months and caecal reservoir 132 months 
 Drop‐outs: Only 56 patients of previous total 94 patients presented, no reason given. 38 drop‐outs
Kristjansson 1995b 
 Mean follow‐up: 150 months 
 Drop‐outs: 5 patients for renal scarring study, 4 patients in bacteriuria study (patients declined to participate)
Participants Incl: invasive bladder carcinoma, radical cystectomy and neurogenic bladder dysfunction
Mansson 1989 
 n = 94 
 Sex: 71 male, 23 female 
 Mean age: Ileal conduit 60 years, colonic conduit 60 years and caecal reservoir 51 years
Kristjansson 1995a (primary reference) 
 n = 56 
 Sex: 43 male, 13 female 
 Mean age: Ileal conduit 60 years, colonic conduit 60 years, caecal reservoir 50 years
Kristjansson 1995b 
 n (renal scarring) = 32 
 n (bacteriuria) = 5 
 n (GFR in renal units with scarring) = 60 
 Sex: (no mention) 
 Mean age: (no mention)
Interventions I: Ileal conduit diversion ‐ refluxing 
 II: Ileal conduit diversion ‐ non ‐ refluxing 
 III: Colonic conduit diversion ‐ refluxing 
 IV: Colonic conduit diversion ‐ non ‐ refluxing 
 V: Caecal continent diversion ‐ non ‐ refluxing
Outcomes Mansson 1989 
 I: Renal function ‐ glomerular filtration rate 
 II: Ureterointestinal anastomotic strictures 
 III: Urinary tract infections
Kristjansson 1995a (primary reference) 
 I: Renal function: glomerular filtration rate 
 II: Ureterointestinal anastomotic strictures 
 III: Urinary tract infections
Kristjansson 1995b 
 I: Renal scarring: Presence and grade (1‐3) 
 II: Bacteriuria: Presence and location 
 III: GFR in renal units with scarring
Notes Further follow‐up presented by Kristjansson in 1995
Kristjansson 1995a was used as the primary study as this had a longer follow‐up compared to Mansson 1989
The outcomes in Kristjansson 1995b of the presence and location of bacteriuria were not included as the numbers who participated were very small: 3 with ileal conduit and 2 with colonic conduit.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk not stated
Allocation concealment (selection bias) Unclear risk not stated
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk not stated
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk not stated
Incomplete outcome data (attrition bias) 
 All outcomes High risk In 10 patients the initial allocation to colonic conduit was changed to ileal because of colonic anomalies. To minimize imbalance between the two conduit groups, each case following an unplanned ileal diversion received a colonic conduit