Source	Search strategy	Hits retrieved
Cochrane Vascular Specialised Register via the Cochrane Register of Studies	#1 MESH DESCRIPTOR Pulmonary Embolism EXPLODE ALL AND INREGISTER #2 MESH DESCRIPTOR Thromboembolism EXPLODE ALL AND INREGISTER #3 MESH DESCRIPTOR Thrombosis EXPLODE ALL AND INREGISTER #4 MESH DESCRIPTOR Venous Thromboembolism EXPLODE ALL AND INREGISTER #5 MESH DESCRIPTOR Venous Thrombosis EXPLODE ALL AND INREGISTER #6 (vein* or ven*) adj thromb* AND INREGISTER #7 blood adj3 clot* AND INREGISTER #8 deep vein thrombosis AND INREGISTER #9 lung adj3 clot* AND INREGISTER #10 PE or DVT or VTE AND INREGISTER #11 peripheral vascular thrombosis AND INREGISTER #12 post‐thrombotic syndrome AND INREGISTER #13 pulmonary embolism AND INREGISTER #14 pulmonary adj3 clot* AND INREGISTER #15 thrombus* or thrombopro* or thrombotic* or thrombolic* or thromboemboli* or thrombos* or embol* or microembol* AND INREGISTER #16 venous thromboembolism AND INREGISTER #17 #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 #18 below the knee AND INREGISTER #19 cDVT AND INREGISTER #20 ICMVT AND INREGISTER #21 IDDVT AND INREGISTER #22 infrapopliteal deep veins AND INREGISTER #23 calf AND INREGISTER #24 distal AND INREGISTER #25 #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 #26 #25 AND #17	360
CENTRAL via CRSO	#1 MESH DESCRIPTOR Pulmonary Embolism EXPLODE ALL TREES 890 #2 MESH DESCRIPTOR Thromboembolism EXPLODE ALL TREES 1784 #3 MESH DESCRIPTOR Thrombosis EXPLODE ALL TREES 4275 #4 MESH DESCRIPTOR Venous Thromboembolism EXPLODE ALL TREES 479 #5 MESH DESCRIPTOR Venous Thrombosis EXPLODE ALL TREES 2413 #6 (((vein* or ven*) adj thromb*)):TI,AB,KY 8171 #7 (blood adj3 clot*):TI,AB,KY 3981 #8 (deep vein thrombosis):TI,AB,KY 3534 #9 (lung adj3 clot*):TI,AB,KY 7 #10 (PE or DVT or VTE):TI,AB,KY 5333 #11 (peripheral vascular thrombosis):TI,AB,KY 0 #12 (post‐thrombotic syndrome):TI,AB,KY 133 #13 (pulmonary embolism):TI,AB,KY 2206 #14 (pulmonary adj3 clot*):TI,AB,KY 10 #15 (thrombus* or thrombopro* or thrombotic* or thrombolic* or thromboemboli* or thrombos* or embol* or microembol*):TI,AB,KY 23686 #16 (venous thromboembolism):TI,AB,KY 2471 #17 #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 30248 #18 (below the knee):TI,AB,KY 173 #19 cDVT:TI,AB,KY 2 #20 ICMVT:TI,AB,KY 1 #21 IDDVT:TI,AB,KY 4 #22 (infrapopliteal deep veins):TI,AB,KY 0 #23 calf:TI,AB,KY 1451 #24 distal:TI,AB,KY 8172 #25 #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 9724 #26 #17 AND #25 901	901
MEDLINE (Ovid MEDLINE Epub Ahead of Print, In‐Process & Other Non‐Indexed Citations, Ovid MEDLINE Daily and Ovid MEDLINE) 1946 to present 2017, 2018 and 2019 only	1 Pulmonary Embolism/ 2 Thromboembolism/ 3 Thrombosis/ 4 exp Venous Thromboembolism/ 5 exp Venous Thrombosis/ 6 ((vein* or ven*) adj thromb*).ti,ab. 7 (blood adj3 clot*).ti,ab. 8 deep vein thrombosis.ti,ab. 9 (lung adj3 clot*).ti,ab. 10 (PE or DVT or VTE).ti,ab. 11 peripheral vascular thrombosis.ti,ab. 12 post‐thrombotic syndrome.ti,ab. 13 pulmonary embolism.ti,ab. 14 (pulmonary adj3 clot*).ti,ab. 15 (thrombus* or thrombopro* or thrombotic* or thrombolic* or thromboemboli* or thrombos* or embol* or microembol*).ti,ab. 16 venous thromboembolism.ti,ab. 17 or/1‐16 18 "below the knee".ti,ab. 19 cDVT.ti,ab. 20 ICMVT.ti,ab. 21 IDDVT.ti,ab. 22 "infrapopliteal deep veins".ti,ab. 23 calf.ti,ab. 24 distal.ti,ab. 25 or/18‐24 26 17 and 25 27 randomized controlled trial.pt. 28 controlled clinical trial.pt. 29 randomized.ab. 30 placebo.ab. 31 drug therapy.fs. 32 randomly.ab. 33 trial.ab. 34 groups.ab. 35 or/27‐34 36 exp animals/ not humans.sh. 37 35 not 36 38 26 and 37 39 (2017* or 2018* or 2019*).ed. 40 38 and 39 41 from 40 keep 1‐244	244
Embase 2017, 2018 and 2019 only	1 lung embolism/ 2 thromboembolism/ 3 thrombosis/ 4 exp venous thromboembolism/ 5 exp vein thrombosis/ 6 ((vein* or ven*) adj thromb*).ti,ab. 7 (blood adj3 clot*).ti,ab. 8 deep vein thrombosis.ti,ab. 9 (lung adj3 clot*).ti,ab. 10 (PE or DVT or VTE).ti,ab. 11 peripheral vascular thrombosis.ti,ab. 12 post‐thrombotic syndrome.ti,ab. 13 pulmonary embolism.ti,ab. 14 (pulmonary adj3 clot*).ti,ab. 15 (thrombus* or thrombopro* or thrombotic* or thrombolic* or thromboemboli* or thrombos* or embol* or microembol*).ti,ab. 16 venous thromboembolism.ti,ab. 17 or/1‐16 18 "below the knee".ti,ab. 19 cDVT.ti,ab. 20 ICMVT.ti,ab. 21 IDDVT.ti,ab. 22 "infrapopliteal deep veins".ti,ab. 23 calf.ti,ab. 24 distal.ti,ab. 25 or/18‐24 26 17 and 25 27 randomized controlled trial/ 28 controlled clinical trial/ 29 random$.ti,ab. 30 randomization/ 31 intermethod comparison/ 32 placebo.ti,ab. 33 (compare or compared or comparison).ti. 34 ((evaluated or evaluate or evaluating or assessed or assess) and (compare or compared or comparing or comparison)).ab. 35 (open adj label).ti,ab. 36 ((double or single or doubly or singly) adj (blind or blinded or blindly)).ti,ab. 37 double blind procedure/ 38 parallel group$1.ti,ab. 39 (crossover or cross over).ti,ab. 40 ((assign$ or match or matched or allocation) adj5 (alternate or group$1 or intervention$1 or patient$1 or subject$1 or participant$1)).ti,ab. 41 (assigned or allocated).ti,ab. 42 (controlled adj7 (study or design or trial)).ti,ab. 43 (volunteer or volunteers).ti,ab. 44 trial.ti. 45 or/27‐44 46 26 and 45 47 (2017* or 2018* or 2019*).em. 48 46 and 47	747
CINAHL 2017, 2018 and 2019 only	S42 S40 AND S41 S41 EM 2017 OR EM 2018 OR EM 2019 S40 S26 AND S39 S39 S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 S38 MH "Random Assignment" S37 MH "Single‐Blind Studies" or MH "Double‐Blind Studies" or MH "Triple‐Blind Studies" S36 MH "Crossover Design" S35 MH "Factorial Design" S34 MH "Placebos" S33 MH "Clinical Trials" S32 TX "multi‐centre study" OR "multi‐center study" OR "multicentre study" OR "multicenter study" OR "multi‐site study" S31 TX crossover OR "cross‐over" S30 AB placebo* S29 TX random* S28 TX trial* S27 TX "latin square" S26 S17 AND S25 S25 S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 S24 TX distal S23 TX calf S22 TX infrapopliteal deep veins S21 TX IDDVT S20 TX ICMVT S19 TX cDVT S18 TX below the knee S17 S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 S16 TX venous thromboembolism S15 TX thrombus* or thrombopro* or thrombotic* or thrombolic* or thromboemboli* or thrombos* or embol* or microembol* S14 TX pulmonary n3 clot* S13 TX pulmonary embolism S12 TX post‐thrombotic syndrome S11 TX peripheral vascular thrombosis S10 TX PE or DVT or VTE S9 TX lung n3 clot* S8 TX deep vein thrombosis S7 TX blood n3 clot* S6 TX ((vein* or ven*) n thromb*) S5 (MH "Venous Thrombosis+") S4 (MH "Venous Thromboembolism") S3 (MH "Thrombosis") S2 (MH "Thromboembolism") S1 (MH "Pulmonary Embolism")	50
Clinicaltrials.gov	below the knee OR distal OR calf | Interventional Studies | Venous Thromboembolism OR Venous Thrombosis OR Pulmonary Embolism OR deep vein thrombosis OR DVT	94
ICTRP Search Portal	below the knee OR distal OR calf | Venous Thromboembolism OR Venous Thrombosis OR Pulmonary Embolism OR deep vein thrombosis OR DVT	18