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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Epilepsia. 2019 Oct 6;60(11):2286–2293. doi: 10.1111/epi.16352

TABLE 3.

Relationship between genetic causal attribution and IES score

Unadjusted Adjusted
Predictor % High IES N PR (95% CI) P PR (95% CI) P
Chance you have a change or mutation in a gene that affects risk for epilepsy
 High chance 56.5 62 2.1 (0.98–4.68) .05 2.3 (0.85–6.11) .10
 Moderate chance 53.1 32 2.0 (0.89–4.57) .09 2.1 (0.77–5.60) .15
 No/small chance 26.3 19 1.0 (ref) (ref) 1.0 (ref) (ref)
Total n 113
Role of genetics in causing epilepsy in your family
 Big role 55.1 89 1.6 (0.95–2.54) .08 1.8 (1.07–2.98) .03
 Medium 50.0 42 1.4 (0.81–2.44) .22 1.6 (0.92–2.90) .09
 No/small 35.5 31 1.0 (ref) (ref) 1.0 (ref) (ref)
Total n 162
Influence of genetics in causing your epilepsy
 Strong influence 53.6 97 1.4 (0.74–2.58) .32 1.0 (0.53–1.92) .97
 Some influence 51.2 43 1.3 (0.69–2.51) .41 0.9 (0.46–1.71) .73
 No influence 38.9 18 1.0 (ref) (ref) 1.0 (ref) (ref)
Total n 158
Genetic attribution scale n/a 165 1.4 (1.04–1.77) .03 1.4 (1.07–1.91) .01

Note: Outcome is relative to “low IES” (<1.5). Total numbers vary based on missing data. Adjusted models include time since last seizure (≤5 years, >5 years) and total lifetime number of seizures (≤20, 21–100, >100).

Abbreviations: CI, confidence interval; IES, Impact of Epilepsy Scale; PR, prevalence ratio; ref, referent.