TABLE 3.
Relationship between genetic causal attribution and IES score
Unadjusted | Adjusted | |||||
---|---|---|---|---|---|---|
Predictor | % High IES | N | PR (95% CI) | P | PR (95% CI) | P |
Chance you have a change or mutation in a gene that affects risk for epilepsy | ||||||
High chance | 56.5 | 62 | 2.1 (0.98–4.68) | .05 | 2.3 (0.85–6.11) | .10 |
Moderate chance | 53.1 | 32 | 2.0 (0.89–4.57) | .09 | 2.1 (0.77–5.60) | .15 |
No/small chance | 26.3 | 19 | 1.0 (ref) | (ref) | 1.0 (ref) | (ref) |
Total n | 113 | |||||
Role of genetics in causing epilepsy in your family | ||||||
Big role | 55.1 | 89 | 1.6 (0.95–2.54) | .08 | 1.8 (1.07–2.98) | .03 |
Medium | 50.0 | 42 | 1.4 (0.81–2.44) | .22 | 1.6 (0.92–2.90) | .09 |
No/small | 35.5 | 31 | 1.0 (ref) | (ref) | 1.0 (ref) | (ref) |
Total n | 162 | |||||
Influence of genetics in causing your epilepsy | ||||||
Strong influence | 53.6 | 97 | 1.4 (0.74–2.58) | .32 | 1.0 (0.53–1.92) | .97 |
Some influence | 51.2 | 43 | 1.3 (0.69–2.51) | .41 | 0.9 (0.46–1.71) | .73 |
No influence | 38.9 | 18 | 1.0 (ref) | (ref) | 1.0 (ref) | (ref) |
Total n | 158 | |||||
Genetic attribution scale | n/a | 165 | 1.4 (1.04–1.77) | .03 | 1.4 (1.07–1.91) | .01 |
Note: Outcome is relative to “low IES” (<1.5). Total numbers vary based on missing data. Adjusted models include time since last seizure (≤5 years, >5 years) and total lifetime number of seizures (≤20, 21–100, >100).
Abbreviations: CI, confidence interval; IES, Impact of Epilepsy Scale; PR, prevalence ratio; ref, referent.