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. 2020 Apr 9;15(4):e0231220. doi: 10.1371/journal.pone.0231220

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© 2020 Xie et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — Open circles, C57BL/6J mice; closed circles, Rdh5^-/- mice. Panel A, thickness changes in the inner retinal layer (layer A). Panel B, the thickness of the outer retinal layer (layer B). Panel C, the thickness of the photoreceptor inner and outer segments (IS/OS) layer (layer C). Panel D, the thickness of the combined RPE and choroid layers (layer D). Animal numbers: C57BL/6J mice, n = 4 (PM1-4), n = 6 (PM5 and 6); Rdh5^-/- mice, n = 6 (PM1-3 and PM6), n = 8 (PM4), n = 4 (PM5). Statistical significance: *, P <0.05; **, P <0.01; ***, P < 0.001 (Student’s t-test).