Table 5. Correlation of validated miRNAs by RT-qPCR with clinical parameters.
| Parameters | miR-374b-5p | miR-199a-5p | miR-125b-5p | miR-30e-3p | miR-126-3p | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| r | p-value | r | p-value | r | p-value | r | p-value | r | p-value | |
| Z-Scores of Cardiac Structures | - | ns | - | ns | - | ns | - | ns | - | ns |
| IVSd | - | ns | - | ns | -0.39 | 0.0243 | - | ns | - | ns |
| IVSs | - | ns | - | ns | - | ns | - | ns | - | ns |
| LVIDd | - | ns | 0.38 | 0.0352 | - | ns | - | ns | - | ns |
| LVIDs | - | ns | - | ns | - | ns | - | ns | - | ns |
| LVPWd | - | ns | - | ns | - | ns | - | ns | - | ns |
| LVPWs | - | ns | - | ns | - | ns | - | ns | - | ns |
| Z-Scores of the Aorta | - | ns | - | ns | - | ns | - | ns | - | ns |
| Aortic Valve | - | ns | - | ns | - | ns | - | ns | - | ns |
| Sinuses | - | ns | - | ns | - | ns | - | ns | - | ns |
| Sinotubular Junction | - | ns | - | ns | - | ns | - | ns | 0.42 | 0.0154 |
| Ascending Aorta | - | ns | - | ns | - | ns | - | ns | - | ns |
| EDV (BSA) [ml/m2] | 0.40 | 0.0303 | - | ns | - | ns | - | ns | - | ns |
| ESV (BSA) [ml/m2] | - | ns | - | ns | - | ns | - | ns | - | ns |
| SV (BSA) [ml/m2] | - | ns | - | ns | - | ns | - | ns | - | ns |
| EF [%] | - | ns | - | ns | - | ns | - | ns | 0.37 | 0.0348 |
| FS [%] | - | ns | - | ns | - | ns | - | ns | 0.37 | 0.0356 |
| LV Mass (BSA) [g/m2] | - | ns | - | ns | - | ns | - | ns | - | ns |
| MAPSE [mm] | 0.39 | 0.0368 | - | ns | - | ns | - | ns | 0.42 | 0.0150 |
| SBP [mmHg] | - | ns | - | ns | - | ns | - | ns | - | ns |
| DBP [mmHg] | 0.37 | 0.0498 | - | ns | - | ns | 0.37 | 0.0362 | 0.37 | 0.0364 |
IVSd, interventricular septum thickness at end-diastole; IVSs, interventricular septum thickness at end-systole; LVIDd, left ventricular internal dimension at end-diastole; LVIDs, left ventricular internal dimension at end-systole; LVPWd, left ventricular posterior wall thickness at end-diastole; LVPWs, left ventricular posterior wall thickness at end-systole; EDV, left ventricular end-diastolic volume; ESV, left ventricular end-systolic volume; SV, stroke volume; EF, ejection fraction; FS, fractional shortening, LV Mass, left ventricular end-diastolic mass, MAPSE, mitral annular plane systolic excursion, SBP, systolic blood pressure, DBP, diastolic blood pressure, ns, non-significant, p-value <0.05.