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. 2020 Feb 24;7(2):e00325. doi: 10.14309/crj.0000000000000325

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© 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.

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Figure 2. — Histopathologic images of the patient's acute liver injury from liver biopsy showing (A) there is severe acute hepatitis, consistent with an Epstein-Barr virus-driven hepatitis. There is a marked mixed portal and lobular inflammatory infiltrate showing numerous inflammatory cells in the hepatic sinusoids. Marked cholestasis is present, and apoptotic hepatocytes are present (hematoxylin & eosin stain 200×). (B) Highlighted scattered nuclear staining in the lymphocytes, which is compatible with Epstein-Barr virus infection (hematoxylin & eosin stain 400×).