Table 1.
Correlation between the clinicopathologic variables and hsa_circ_0091581 expression in HCC tissues.
| Variables | Case | hsa_circ_0091581 expression low/high | P value |
|---|---|---|---|
| Gender | |||
| Male | 41 | 19/22 | |
| Female | 5 | 4/1 | 0.173 |
| Age (y) | |||
| ≤60 | 37 | 18/19 | |
| >60 | 9 | 5/4 | 0.336 |
| TNM stage | |||
| I | 39 | 21/18 | |
| II–III | 7 | 2/5 | 0.207 |
| Tumor size (cm) | |||
| ≤5 | 32 | 21/11 | |
| >5 | 14 | 2/14 | 0.002 |
| Tumor number | |||
| 1 | 33 | 19/14 | |
| ≥2 | 13 | 4/9 | 0.095 |
| AFP (ng/mL) | |||
| ≤20 | 21 | 13/8 | |
| >20 | 25 | 10/15 | 0.118 |
| ALT(U/L) | |||
| ≤40 | 40 | 20/20 | |
| >40 | 6 | 3/3 | 0.667 |
| Liver cirrhosis | |||
| Yes | 6 | 2/4 | |
| No | 40 | 21/19 | 0.333 |
| HBV | |||
| Negative | 5 | 2/3 | |
| Positive | 41 | 21/20 | 0.500 |
hsa_circ_0091581 expression low/high: the expression of hsa_circ_0091581 in HCC tissues was lower/higher than the median; AFP: alpha-fetoprotein; ALT, alanine aminotransferase; HBV: hepatitis B virus.