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. 2020 Feb 23;19(6):684–696. doi: 10.1080/15384101.2020.1717041

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Figure 1. — Sevoflurane up-regulates PTEN expression and silencing of PTEN reverses the inhibitory effect of sevoflurane by activating MEK1/ERK signaling pathway in hippocampal tissues of infant rats. A. PTEN expression in hippocampal tissues of infant rats in each group; B. Protein band of PTEN in hippocampal tissues of infant rats in each group; C. PTEN protein expression in hippocampal tissues of infant rats in each group; D. Protein bands of MEK1/ERK signaling pathway-related factors in hippocampal tissues of infant rats in each group; E. Protein expression of MEK1/ERK signaling pathway-related factors in hippocampal tissues of infant rats in each group; the data in the figure were measurement data and expressed by mean ± standard deviation. Comparisons among multiple groups used one-way ANOVA and verified by Tukey’s post hoc test. n = 10; * P < 0.05 compared with the normal group; # P < 0.05 compared with the Sevo group.