Table 2. Best fit parameters of all models.
| Models presented in main figures | |||
|---|---|---|---|
| Single-sensor model (Figure 4) | Dual fusion-sensor model, cooperativity 2 (Figure 6) | Unpriming model, cooperativity 5 (Figure 7) | |
| Qmax | 8.42 fC | 4.51 fC | 13.77 fC |
| krep | 165.53 s−1 | 159.30 s−1 | 134.85 s−1 |
| nsites | 216 | 211 | 180 |
| k2 | 4.10e7 M−1s−1 | ||
| s | 510.26 | ||
| u | 236.82 s−1 | ||
| kM,prim | 55.21 nM−1 | ||
| Cost value (see Materials and methods) | 9.689 | 4.129 | 0.340 |
| Models presented in figure supplements | |||
| Dual fusion-sensor model, cooperativity 5 (Figure 6—figure supplement 1) | Unpriming model, cooperativity 2 (Figure 7—figure supplement 1) | Site activation model (Figure 7—figure supplement 3) | |
| Qmax | 8.10 fC | 13.49 fC | 12.59 fC |
| krep | 492.56 s−1 | 106.59 s−1 | 141.20 s−1 |
| nsites | 112 | 203 | 189 |
| k2 | 5.41e6 M−1s−1 | ||
| s | 261.07 | ||
| u | 5207.70 s−1 | ||
| kM,prim | 7.61 nM−1 | ||
| β | 0.09 s−1 | ||
| γ | 194.77 s−1 | ||
| δ | 10.70 s−1 | ||
|
Cost value
(see Materials and methods) |
2.941 | 0.642 | 1.57 |