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. 2020 Apr 2;46(4):84–92. doi: 10.14745/ccdr.v46i04a05

Table 5. Criteria recommended by 2017 ATS Guidelines for rapid molecular drug susceptibility testing for rifampina.

Criteria All TB patientsb DS-TB Non-MDR/RMP drug resistance MDR/RMP-R TB MDR/RMP-R TB vs DS-TB MDR/RMP-R TB vs non-MDR/RMP drug resistance
(n=485) % (n=306) % (n=49) % (n=47) % OR (95% CI) p-value OR (95% CI) p-value
Previous TB treatment 70 14.4 26 8.5 9 18.4 16 34.0 5.39 (2.57–11.3) <0.001 2.21 (0.83–5.90) 0.112
Born or lived less than one year in higher risk country 428 88.2 264 86.3 43 87.8 45 95.7 2.72 (0.62–11.2) 0.184 3.02 (0.56–16.2) 0.197
Contact of MDR-TB 4 0.8 1 0.3 2 4.1 1 2.1 9.04 (0.54–148.7) 0.123 0.46 (0.03–5.60) 0.548
HIV infection 10 2.1 6 2.0 0 0.0 4 8.5 4.26 (1.06–17.0) 0.04 N/A N/A N/A

Abbreviations: ATS, American Thoracic Society; DS, drug-susceptible; HIV, human immunodeficiency virus; MDR, multidrug resistant; N/A, not applicable; R, resistance, RMP, rifampin; TB, tuberculosis

a Rapid molecular drug susceptibility testing for rifampin by drug resistance pattern (A) and multivariable analyses comparing MDR/RMP-R TB with drug susceptible TB (B) and non-MDR/RMP drug resistant TB (C)

b TB incidence of ≥20/100,000 or primary MDR prevalence of ≥2%