Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 14;48(1):421–431. doi: 10.1093/nar/gkz1037

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — CtCfp1 marginally activates COMPASS methyltransferase activity in vitro. (A) Reconstitution of COMPASS with CtCfp1. COMPASS was incubated with a 5-molar ratio of CtCfp1 and separated on a superpose 6. The panel shows the chromatogram of COMPASS separated in presence (dotted line) or absence of CtCfp1 (full line). (B) CtCfp1 modestly activates the methyltransferase activity of COMPASS on the nucleosome core particle. The error bars indicate the standard deviation of two biological replicates performed in triplicates. (C) CtCfp1 modestly activates the methyltransferase activity of COMPASS on peptides. Table showing the kinetic parameters obtained with the michealis-menten plots for H3K4me0 (D), H3K4me1 (E) and H3K4me2 (F) peptides.