Table 2.
Overview of the most popular searches and tools available at AFND
| Polymorphic region | Tool | Description |
|---|---|---|
| HLA | Classical and non-classical allele frequency search | Querying tool to explore allele and phenotype frequencies in one or many populations from the given criteria. |
| Haplotype frequency search | Tool to consult a particular haplotype in a set of populations at two or more loci. | |
| Rare HLA alleles search | Section to ascertain the rarity of HLA alleles based on the confirmation from different databases and individual laboratories. | |
| Amino acid frequencies in populations | Interactive tool to examine frequencies in a given population comparing alleles differing at amino acid positions. | |
| Lower resolution search+ | Tool to search for low resolution data from a given high resolution allele. | |
| Allele survey+ | This tool provides a summary of statistical information regarding that allele, based on our Gold Standard populations, which are organized by geographical regions. | |
| Genotype data browser+ | Searching mechanism to explore genotype raw data submitted via the short population reports. | |
| KIR | Allele frequency search | Querying tool to explore allele and phenotype frequencies in one or many populations from the given criteria. |
| Genotype frequency search | Tool which allows users to display genotype frequencies of a given profile. | |
| Cell-lines and CEPH families | Section that provides a reference of KIR cell-lines and Centre d' Etude du Polymorphisme Humain (CEPH) families typed at allele level. | |
| Linkage disequilibrium (LD) analysis+ | Tool for the analysis of LD among KIR genes by population, country, geographical region and ethnicity. | |
| Cytokines | Cytokine frequency search | Querying tool to explore allele frequencies in one or many populations from the given criteria. |
| MIC | Allele frequency search | Querying tool to explore allele and phenotype frequencies in one or many populations from the given criteria. |
| MIC-HLA association frequency search | Section that provides frequencies of MIC and HLA associations. | |
| Online submissions | Populations | Online submission tool for a new population. |
| Confirmation of rare alleles | Section for the confirmation of rare HLA alleles. |
+New tools and searches since 2015.