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RET mutation. Somatic RET mutations in sporadic medullary thyroid cancer (MTC) and among different multiple endocrine neoplasia type 2 (MEN2) phenotypes are shown. The frequencies of somatic mutations are derived from the COSMIC database. The frequencies of mutations in MEN2 are derived from published studies.44a-d FMTC, familial medullary thyroid carcinoma.
