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. 2019 Oct 31;48(D1):D198–D203. doi: 10.1093/nar/gkz1028

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — A case application showing select SEA v. 3.0 features. (A) Super-enhancers with related coding genes computationally recognized by p300 in chromosome 1 of the human HepG2 cell line. (B) Enrichment analysis of super-enhancer related genes through the Enrichr interface. (C) Cell type specificity of super-enhancers computed by Shannon Entropy. (D) H3K27ac, p300 and Brd4 density of HepG2 super-enhancers visualized in the genome browser. (E) Spatial interaction visualization by Hi-C in the genome region ‘chr1:156864585–156975979’.