Table 3.
Data availability summary for top tier pathogens. Summary of target data available for Tier 1 organisms in TDR Targets. CDS: Coding sequences; PFAM: number of proteins with mapped Pfam domain(s); GO: number of proteins with mapped Gene Ontology terms; EC: number of proteins with mapped Enzyme Commission (EC) numbers; Pathways: number of proteins mapped to KEGG pathway maps; Orthologs: number of sequences mapped to OrthoMCL ortholog groups. A more complete data summary table is available online at https://tdrtargets.org/datasummary
| Species | CDS | PFAM | GO | EC | Pathways | Orthologs |
|---|---|---|---|---|---|---|
| Plasmodium falciparum | 5349 | 3322 | 3551 | 750 | 1083 | 5166 |
| Plasmodium vivax | 5344 | 3264 | 2631 | 641 | 806 | 5207 |
| Toxoplasma gondii | 7946 | 4025 | 3795 | 772 | 967 | 6764 |
| Chlamydia trachomatis | 887 | 704 | 598 | 269 | 357 | 645 |
| Mycobacterium leprae | 1630 | 1236 | 929 | 628 | 611 | 1473 |
| Mycobacterium tuberculosis | 4004 | 2934 | 2001 | 1174 | 1145 | 3287 |
| Mycobacterium ulcerans | 4232 | 3602 | 2578 | 873 | 1002 | 3459 |
| Treponema pallidum | 1036 | 791 | 634 | 221 | 335 | 733 |
| Wolbachia endosymbiont of B. malayi | 805 | 628 | 577 | 308 | 382 | 688 |
| Brugia malayi | 11316 | 7042 | 6368 | 1278 | 1787 | 8424 |
| Echinococcus granulosus | 10249 | 6481 | 5432 | 854 | 1965 | 7109 |
| Echinococcus multilocularis | 10474 | 6817 | 5768 | 878 | 2079 | 7539 |
| Loa Loa (eye worm) | 16292 | 8071 | 6774 | 1539 | 2207 | 10484 |
| Onchocerca volvulus | 12224 | 3248 | 2178 | 246 | 563 | 4054 |
| Schistosoma mansoni | 12692 | 7818 | 7384 | 1218 | 1649 | 10386 |
| Leishmania major | 8280 | 4641 | 4415 | 1067 | 1162 | 8250 |
| Trypanosoma brucei | 10270 | 5665 | 5482 | 1019 | 1264 | 9259 |
| Trypanosoma cruzi | 18639 | 9908 | 8572 | 1495 | 1735 | 18140 |
| Entamoeba histolytica | 8211 | 4920 | 4087 | 645 | 1094 | 7692 |
| Giardia lamblia | 9665 | 2726 | 2263 | 326 | 514 | 5977 |
| Trichomonas vaginalis | 95600 | 35474 | 18435 | 843 | 1366 | 87303 |