Table 3.

Coverage and recovery rate of core pathways, extended pathways using only experimental PPIs, and extended pathways using full (combination of experimental and predicted) PPIs for human proteins (top row) and their pathway memberships (bottom row) in pathDIP 4.

Human pathways	Curated	Extended using experimental PPIs (0.95)	Extended using experimental and predicted PPIs (0.95)
Coverage for protein-coding genes	65%	89%	92%
Recovery for known pathway members	-	59%	87%

Extended pathways are based on 95% confidence cut-off.