Figure 1.

Multiple correspondence analysis of the reaction presence or absence within each model clusters models according to eukaryotic (yellow ellipse), prokaryotic (green ellipse and inset) and photosynthetic eukaryotes (blue ellipse) within metabolic reaction space. Dimension 1 (x-axis) explained 14.5% of the variance; dimension 2 (y-axis) explained 14.2%. Further, a number of the models newly introduced within this update (red circles) are found at edges of the MCA plot, indicating that within these two dimensions, they contribute to additional diversity in reaction content compared to the previous release. For this analysis, iML1515 was used as a representative E. coli model and iIS312 as representative for Trypanosoma cruzi.