Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 14;47(22):11755–11770. doi: 10.1093/nar/gkz992

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 3. — Uncompleted double-strand repair and synapsis. (A) Spread spermatocytes from Fbxo47^+/+ and Fbxo47^−/− males were immunostained with anti-SYCP3 and anti-γ-H2AX antibodies. Arrows indicate the sex body; Arrowheads indicate impaired double-strand repair. Scale bars, 10 μm. (B) Spread spermatocytes from Fbxo47^+/+ and Fbxo47^−/− males were immunostained for synaptonemal complex proteins (SYCP3 and SYCP1). Scale bars, 10 μm. (C) Frequencies of meiotic stages in testes from 8-week-old mice with the indicated genotypes. SYCP3-positive spermatocytes (889 cells were counted) are classified into the following substages: Lep, leptotene (no SYCP1); Zyg, zygotene (partially assembled SYCP1); Pac, pachytene (fully assembled SYCP1); Dip, diplotene (disassembled SYCP1); Met I, metaphase I (no SYCP1 and SYCP3 accumulation at centromeres). Mean values of three independent experiments from three different mice are shown. Error bars, SEM (n = 3).