Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 16;48(1):460–471. doi: 10.1093/nar/gkz1081

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 5. — R3 repeat is incompatible with DNA 6mA modification. (A) The interactions between R3 Asn residues and the AA element in WER–DNA and MsMyb–DNA (PDB code: 1H8A) complexes. ITC analysis shows the impact of 6mA modification on DNA binding by (B) WER and (C) MsMyb, respectively. (D) Consensus sequence and conservation analysis of the R3 motif involved in DNA recognition of MYB domain proteins. Plant and animal MYB proteins are shown in the upper and lower panels, respectively. (E) The potential target motif AACNDN (D: A or T or G) recognized by WER can be methylated in vivo by searching the Arabidopsis DNA methylation databases (GSM2807190 for 5mC, GSM2157793 for 6mA).