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. 2019 Nov 13;47(22):11637–11648. doi: 10.1093/nar/gkz1040

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Crystal structure of the LmaH3 nucleosome. (A) Overall crystal structure of the LmaH3 nucleosome. The LmaH3 molecules are colored cyan, and the LmaH3-specific residues are shown as magenta with side chains. The LmaH3-specific Trp35, Gln57 and Met98 residues are indicated in magenta letters. The Trp35, Gln57 and Met98 residues from the other LmaH3 molecule are labeled with prime (′). (B) Superimposition of the H3.1 (PDB ID: 3AFA) and LmaH3 structures in the nucleosomes. H3.1 and LmaH3 are colored green and cyan, respectively. The LmaH3-specific residues are colored magenta. (C–H) Close-up views of the H3.1 Tyr41, Arg63 and Phe104 residues, corresponding to the LmaH3 Trp35, Gln57 and Met98 residues.