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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Hypertension. 2020 Mar 23;75(5):1315–1324. doi: 10.1161/HYPERTENSIONAHA.120.14736

Figure 6.

Figure 6.

Maternal CAP treatment improves gut pathology in SHR male offspring. (A) Representative hematoxylin-eosin (H&E) and Masson-trichrome staining images of proximal colon of indicated rat groups. (B-E) Quantitative analysis of Masson-trichrome staining to demonstrate the fibrotic area in the proximal colon. Quantitative analysis of H&E staining to demonstrate the thickness of muscle layer, numbers of goblet cells per 100 epithelial cells and crypt depth in the proximal colon. OCAP, maternal treatment with captopril; SCAP, sustained treatment with captopril. n= 5 rats per group. Data are mean ± SEM. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001 in one-way ANOVA followed by Tukey’s multiple comparison.