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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: J Bone Miner Res. 2020 Jan 6;35(4):725–737. doi: 10.1002/jbmr.3931

Figure 6: Microarray analyses reveals minimal gene expression changes in the NP of hTNFα-TG mice.

Figure 6:

(A) A heat map showing gene and sample clustering of the genotypes in to two distinct groups with more distance between the hTNFα-TG samples than the WT controls. (B) Significance analysis of microarrays (SAM) with a delta value of 0.74 for an FDR of 5%. (C) Volcano plot showing genes with Log2 (fold change) greater than 1 or less than −1 in orange, genes with Log2 (fold change) greater than 1 or less than −1 and adjusted p value < 0.1 in green, and genes with adjusted p value <0.1 in red. (D) PCR verification of genes identified by microarray analysis with significance determine by t-test. (E) A table showing the DAVID identified significant GO biological terms associated with the gene expression changes identified by the microarray. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001.